“Part of a beer name ... or an instruction for answering 53-Across”

Real estate, e.g.

First word of Carroll's "Jabberwocky"

Grps. that are often inactive in the summer

Frida who portrayed her chronic pain through art

Water wheel?

The best of the best

Acrobat developer

"You're in on this?"

Tattle on ... or an instruction for answering 22-Across